Direct orthotopic implantation of hepatic organoids
نویسندگان
چکیده
منابع مشابه
Hepatic organoids for microfluidic drug screening.
We introduce the microfluidic organoids for drug screening (MODS) platform, a digital microfluidic system that is capable of generating arrays of individually addressable, free-floating, three-dimensional hydrogel-based microtissues (or 'organoids'). Here, we focused on liver organoids, driven by the need for early-stage screening methods for hepatotoxicity that enable a "fail early, fail cheap...
متن کاملSafety, Efficacy and Clinical Outcome of Direct Stent Implantation
Conventional methods of stenting require predilatation, which potentially increase vessel wall injury and cost of the procedure. In this study, the safety and efficacy of direct AVE-S7 (Medtronic-USA) stent placement were evaluated in 100 patients. Quantitative coronary angiography was performed at the baseline and post-stent. Clinical follow-up was done up to 9 months. In 100 patients (76 male...
متن کاملHuman hepatic organoids for the analysis of human genetic diseases.
We developed an in vitro model system where induced pluripotent stem cells (iPSCs) differentiate into 3-dimensional human hepatic organoids (HOs) through stages that resemble human liver during its embryonic development. The HOs consist of hepatocytes, and cholangiocytes, which are organized into epithelia that surround the lumina of bile duct-like structures. The organoids provide a potentiall...
متن کاملOrthotopic Liver Transplantation for Etanercept-Induced Acute Hepatic Failure; a case report
The occurrence of hepatotoxicity following etanercept (tumor necrosis factor-alpha antagonist) prescription, has been studied well. However, an acute hepatic failure leading to liver transplant as an adverse effect of this drug has not been reported in the literature. In this article, we are going to present a case of acute liver failure followed by liver transplantation, in a 32 years old man ...
متن کاملHepatic artery thrombosis after orthotopic liver transplantation.
OBJECTIVE Hepatic artery thrombosis after liver transplantation is uncommon, but represents an important cause of morbidity and mortality. The aim of this study is to identify the possible risk factors for the development of hepatic artery thrombosis, and the impact of hepatic artery thrombosis on the patients and graft survival. METHODS Between January 1994 and June 1998, we reviewed retrosp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Surgical Research
سال: 2017
ISSN: 0022-4804
DOI: 10.1016/j.jss.2016.12.028